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#sarscov2

21 posts15 participants3 posts today
Public
Caramelized Shallots

>>Remember COVID toes?... A study has found that people with pandemic chilblains have an unusually strong immune response to single-stranded RNA viruses like SARS-CoV-2, driven by overactive plasmacytoid dendritic cells (pDCs) responding to TLR7 signals. These individuals likely cleared the virus early with innate immunity, before developing antibodies, but the inflammation triggered chilblains in their toes.<<

rupress.org/jem/article/222/7/

drruth.substack.com/p/covid-an

#Covid#Covid19#SarsCoV2
Public
Tove Harris 2. Account

PolyBio-supported study reveals long-term immune and metabolic damage after COVID-19 infection

"New preprint study reveals profound and long-lasting biological disruptions that can follow a SARS-CoV-2 infection, including changes connected to altered metabolism and cancer-associated epigenetic changes."

polybio.org/polybio-supported-

PolyBio Research Foundation · PolyBio-supported study reveals long-term immune and metabolic damage after COVID-19 infection - PolyBio Research FoundationNew preprint study reveals profound and long-lasting biological disruptions that can follow a SARS-CoV-2 infection, including changes connected to altered metabolism...
#COVID#COVID19#Corona
Public
Broadwaybabyto

Excellent article by @nicktsergas about Covid and immunity debt. He interviews many doctors and leading experts to explore whether repeat Covid infections are destroying our immune system.

We must keep reminding people that sarscov2 is a novel virus. It’s only been 5.5 years which is nothing in the lifespan of a brand new disease. We can’t possibly know its true long term implications, and we must have the humility to accept what we don’t know.

The rush “back to normal” and insistence that Covid is “mild” serves the ruling elite. It was shoved down our throat to keep end stage capitalism afloat, not because it was actually mild or over.

What can you do? Wear a mask. Ideally an N95 or better. Clean and ventilate the air. Donate and support local mask blocs. Stay home when you’re sick. Refuse to accept the narrative that anyone is expendable:

canadianaffairs.news/2025/04/0

CANADIAN AFFAIRS · Is COVID quietly sabotaging our immune systems?By Nick Tsergas
#sarscov2#wearamask#covidisairborne
Public
Eric's Risk Assessment

Driving under viral impairment: Linking acute #SARSCoV2 infections to elevated car crash risks | PLOS Global Public Health

> Results demonstrated a significant association between acute #COVID19 infections and an increase in car crashes, independent of #LongCOVID status to the tune of an OR of 1.25 [1.23-1.26]. This association was observed despite varying mitigation efforts and vaccination rates across states. The study found no protective effect of vaccination against car crashes, challenging prior assumptions about the benefits of vaccination. Notably, the risk associated with COVID-19 was found to be analogous to driving impairments seen with alcohol consumption at legal limits.

journals.plos.org/globalpublic

h/t @DickZoutman

journals.plos.orgDriving under viral impairment: Linking acute SARS-CoV-2 infections to elevated car crash risksThis study explores the linkage between acute SARS-CoV-2 and car crashes across U.S. states, correlating with COVID-19 mitigation strategies, vaccination rates, and Long COVID prevalence. This investigation analyzed aggregate COVID-19 and car crash data spanning 2020–2023, with data collection occurring between March and May 2024. Analysis was done via a Poisson regression model, adjusted for population. Key variables included vaccination status, month-specific effects relating to initial pandemic shutdowns, and Long COVID rates. Results demonstrated a significant association between acute COVID-19 infections and an increase in car crashes, independent of Long COVID status to the tune of an OR of 1.25 [1.23-1.26]. This association was observed despite varying mitigation efforts and vaccination rates across states. The study found no protective effect of vaccination against car crashes, challenging prior assumptions about the benefits of vaccination. Notably, the risk associated with COVID-19 was found to be analogous to driving impairments seen with alcohol consumption at legal limits. Findings suggest significant implications for public health policies, especially in assessing the readiness of individuals recovering from COVID-19 to engage in high-risk activities such as pilots or nuclear plant employees. Further research is necessary to establish causation and explore the exact effects of COVID-19 within the CNS affecting cognition and behavior.
#sars2
Public
Tom Kindlon

#LongCovid #PASC

From the Netherlands:

Health outcomes up to 3 years ...

"Specifically, while some health outcomes improved over time, self-reported fatigue and cognitive problems worsened between the second and third year."

thelancet.com/journals/lanepe/

Image is from latest Science for ME weekly update

@longcovid
#PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #SARSCoV2 #CovidIsNotOver

The Lancet Regional Health – Europe Health outcomes up to 3 years and post-exertional malaise in patients after hospitalization for COVID-19: a multicentre prospective cohort study (CO-FLOW) — Julia C. Berentschot et al. "In this multicentre prospective cohort study with follow-up up to 3 years after hospitalization for COVID-19, the findings showed that patient experienced persisting and even worsening of several health issues up to 3 years. Specifically, while some health outcomes improved over time, self-reported fatigue and cognitive problems worsened between the second and third year."
Public
Tom Kindlon

"the results from this analysis suggest among people who were tested for #COVID19, those with a positive test experienced an increased rate of diagnosis of infectious illnesses in the 12 months following"

thelancet.com/journals/laninf/

Image is from latest Science for ME weekly update

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID #COVID_19 #COVIDー19 #SARSCoV2
@auscovid19 #auscovid19

The Lancet Infectious Diseases Rates of infection with other pathogens after a positive COVID-19 test versus a negative test in US veterans (November, 2021, to December, 2023): a retrospective cohort study — Miao Cai et al. "the results from this analysis suggest that among people who were tested for COVID-19, those with a positive test experienced an increased rate of diagnosis of infectious illnesses in the 12 months following"
Public
Tom Kindlon

ICU participants' hospitalisation conferred them status as legitimate patients in ‘medically clear and understandable ways’ whereas LC participants' ‘patienthood’ was neither evidenced nor authenticated"
onlinelibrary.wiley.com/doi/10

Image is from latest Science for ME weekly update

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2

Health Expectations Rethinking ‘Recovery’: A Comparative Qualitative Analysis of Experiences of Intensive Care With COVID and Long Covid in the United Kingdom — Alice MacLean et al. "Key differences in ‘worlds of illness’ stemmed from the fact that ICU participants' hospitalisation conferred them status as legitimate patients in ‘medically clear and understandable ways’ whereas LC participants' ‘patienthood’ was neither evidenced nor authenticated in the same way."
Public
Tom Kindlon

From Germany:

Abnormal Coronary Vascular Response in Patients with #LongCOVID Syndrome – a Case-Control Study Using Oxygenation-Sensitive Cardiovascular Magnetic Resonance

sciencedirect.com/science/arti

Image is from latest Science for ME weekly update

Hashtags:
@longcovid
#PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #CovidIsNotOver
@auscovid19 #auscovid19

1/

Journal of Cardiovascular Magnetic Resonance Abnormal Coronary Vascular Response in Patients with Long COVID Syndrome – a Case-Control Study Using Oxygenation-Sensitive Cardiovascular Magnetic Resonance — Weberling et al. "This pilot study is the first to show a blunted hemodynamic and myocardial oxygenation response to vasoactive breathing maneuvers during Oxygenation-sensitive CMR in long COVID patients. This simple, non-invasive test may be the first to objectify complaints of affected patients and indicates evidence for the crucial role of the endothelium in the pathophysiology of long COVID."
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